Home · Nucleofill Bali — Polynucleotide Skin Booster
A polynucleotide skin booster that improves dermal quality and firmness rather than adding volume. Administered by a board-certified dermatologist, from an authorised distributor.

Authentic, distributor-verified Nucleofill.
Nucleofill is a polynucleotide-based injectable skin booster. It is not a filler and does not add volume — it works by improving the quality of the skin itself, stimulating fibroblast activity and improving hydration and firmness from within the dermis.
It sits alongside Profhilo and Rejuran in the skin booster category, and the three are frequently confused. They do related but distinguishable things.
| Nucleofill | Rejuran | Profhilo | |
|---|---|---|---|
| Base | Polynucleotides | Polynucleotides | Ultra-pure hyaluronic acid |
| Primary effect | Firmness, tightening, dermal quality | Repair, texture, pore refinement | Hydration and bio-remodelling |
| Best suited to | Laxity with thin skin; neck, jawline, under-eye | Damaged, scarred or congested skin | Dry, dull, deflated-looking skin |
| Typical course | A short course, then maintenance | A course of sessions | Two sessions a month apart, then maintenance |
In practice these are often sequenced rather than chosen between. Which comes first depends on whether the dominant problem is quality, repair or hydration — which is a diagnosis, not a preference.
Nucleofill will not lift a descended jawline. If the problem is structural laxity, energy-based tightening such as XERF is the appropriate treatment and a booster will disappoint. It also does not replace lost volume. Being told plainly which problem you have is the point of seeing a specialist.
Counterfeit injectables are a documented concern for patients treated abroad. Elea Clinic sources through authorised Indonesian distributors, and you are welcome to ask to see the sealed packaging and batch details before anything is injected. We would encourage it — at any clinic, not only this one.
Not sure which booster you need?
Send a photograph and describe what bothers you. dr. Jesslyn will tell you which of the three is appropriate — or whether the answer is a different treatment entirely.
Ask dr. Jesslyn Replies Monday–Saturday 9.30am–7pm WITA, usually within 30 minutes.
Nucleofill Strong — polymerised polynucleotide-based gel.

Acne & texture. Individual results vary.

Radiance & glow. Individual results vary.

Skin quality. Individual results vary.
Where can I get Nucleofill in Bali?
At Elea Clinic, Denpasar, administered by dr. Jesslyn Amelia, Sp.D.V.E, a Ministry of Health registered dermatologist. Product is sourced through authorised Indonesian distributors.
What is the difference between Nucleofill and Profhilo?
Nucleofill is polynucleotide-based and works primarily on dermal firmness and skin quality. Profhilo is ultra-pure hyaluronic acid and works primarily on hydration and bio-remodelling. They address related but distinguishable problems and are often sequenced rather than chosen between.
Is Nucleofill the same as Rejuran?
Both are polynucleotide-based. Rejuran is generally directed at repair, texture and pore refinement; Nucleofill at firmness and dermal quality, and it is often used on the neck, jawline and under-eye area.
Will Nucleofill lift my jawline?
No. It improves skin quality and firmness but does not lift structural descent. If the jawline has dropped, energy-based tightening such as XERF is the appropriate treatment.
How do I know the product is genuine?
Ask to see the sealed packaging and batch details before injection. Elea Clinic sources through authorised Indonesian distributors and is happy to show them.
How many sessions will I need?
Typically a short initial course followed by maintenance, but this depends on skin condition and is confirmed at consultation.
Medically reviewed by dr. Jesslyn Amelia, Sp.D.V.E — Dokter Spesialis Dermatologi, Venereologi dan Estetika. Registered with the Indonesian Ministry of Health, STR JT00000382760637. Verify registration. Last reviewed 16 August 2026. Individual results vary; this page is general information and not a substitute for consultation.